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          SCHOOL OF CHEMICAL ENGINEERING

          教師登錄系統

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          教授

          史清洪

          現任職稱/職務:教授
          通訊地址:天津市津南區海河教育園區雅觀路135號 天津大學北洋園校區54樓E363室
          電子郵箱:qhshi@tju.edu.cn
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          代表性論文

          (1) Shi Q. H., Tian Y., Dong X. Y., Bai S., Sun Y. Chitosan-coated silica beads as immobilized metal affinity support for protein adsorption [J]. Biochemical Engineering Journal, 2003, 16 (3): 317-322.

          (2) Shi Q.-H., Zhou Y., Sun Y. Influence of pH and ionic strength on the steric mass-action model parameters around the isoelectric point of protein [J]. Biotechnology Progress, 2005, 21 (2): 516-523.

          (3) Shi Q.-H., Zhou X., Sun Y. A novel superporous agarose medium for high-speed protein chromatography [J]. Biotechnology and Bioengineering, 2005, 92 (5): 643-651.

          (4) Shi Q.-H., Cheng Z., Sun Y. 4-(1H-imidazol-1-yl) aniline: A new ligand of mixed-mode chromatography for antibody purification [J]. Journal of Chromatography A, 2009, 1216 (33): 6081-6087.

          (5) Shi Q.-H., Shen F.-F., Sun S. Studies of Lysozyme Binding to Histamine as a Ligand for Hydrophobic Charge Induction Chromatography [J]. Biotechnology Progress, 2010, 26 (1): 134-141.

          (6) Shi Q.-H., Jia G.-D., Sun Y. Dextran-grafted cation exchanger based on superporous agarose gel: Adsorption isotherms, uptake kinetics and dynamic protein adsorption performance [J]. Journal of Chromatography A, 2010, 1217 (31): 5084-5091.

          (7) Shi Q.-H., Jia G.-D., Sun Y. Process intensification of immobilized metal affinity chromatography with longitudinal and oscillatory transverse electric fields [J]. Separation and Purification Technology, 2011, 77 (3): 375-381.

          (8) Yu L.-L., Shi Q.-H., Sun Y. Effect of dextran layer on protein uptake to dextran-grafted adsorbents for ion-exchange and mixed-mode chromatography [J]. Journal of Separation Science, 2011, 34 (21): 2950-2959.

          (9) Shi Q.-H., Shi Z.-C., Sun Y. Dynamic behavior of binary component ion-exchange displacement chromatography of proteins visualized by confocal laser scanning microscopy [J]. Journal of Chromatography A, 2012, 1257: 48-57.

          (10) Liang J., Fieg G., Shi Q.-H., Sun Y. Single and binary adsorption of proteins on ion-exchange adsorbent: The effectiveness of isothermal models [J]. Journal of Separation Science, 2012, 35 (17): 2162-2173.

          (11) Shi Q.-H., Jia G.-D., Xu L., Sun Y. Effect of electric field on the partitioning behavior of solutes in entropic interaction chromatography [J]. Journal of Separation Science, 2013: doi: 10.1002/jssc.201300297

          論著:

          (1) 史清洪, 趙學明. 產品的回收和純化, in: Shuler M.L., Kargi F. (Eds), Bioprocess Engineering: Basic Concepts (譯), 化工出版社, 北京, 2008, 223-258

          (2) Sun Y., Liu F.-F., Shi Q.-H. Approaches to High-Performance Preparative Chromatography of Proteins. In: Zhong J.-J., Bai F.-W., Zhang W (eds), Biotechnology in China I: From Bioreaction to Bioseparation and Bioremediation. Springer, Heidelberg, 2009, volume 113, 217-254

           (3) Sun Y., Shi Q.-H., Zhang L., Zhao G.-F., Liu F.-F. Downstream Processing and Product Recovery | Adsorption and Chromatography. In: Murray Moo-Young (ed.), Comprehensive Biotechnology (Second Edition), Elsevier, New York, 2011, volume 2, 665–679

          授權專利

          (1) 孫彥,周鑫,史清洪,董曉燕,白姝:高容量大孔瓊脂糖凝膠介質的制備方法,中國發明專利,ZL03130027.8

          (2) 孫彥,周鑫,史清洪,白姝,董曉燕:高密度核材表面包裹瓊脂糖凝膠薄殼介質的制備方法,中國發明專利,ZL 03129755.2

          (3) 孫彥,趙雪雁,張磊,史清洪,董曉燕,白姝:利用膨脹床色素親和色譜純化重組人干擾素α-2b 的方法,中國發明專利,ZL 200310106725.0

          (4) 孫彥,孫國勇,史清洪,董曉燕,白姝:雙乳化法制備兩類孔型剛性高分子介質的方法,中國發明專利,ZL 200410019065.7

          (5) 孫彥,孫國勇,董曉燕,白姝,史清洪:以碳酸鈣微粒懸浮液制備超大孔型剛性高分子介質的方法,中國發明專利,ZL 200510013278.3

          (6) 孫彥,譚國民,史清洪,董曉燕,白姝:制備型橫向電場的體積排阻電色譜分離生物大分子的方法,中國發明專利,ZL 200510014695.X

          (7) 孫彥,王冬梅,史清洪,董曉燕,白姝:超大孔纖維素微球蛋白質吸附介質的制備方法,中國發明專利,ZL 200710056590.X

          (8) 史清洪,程征,孫彥,董曉燕,白姝:用于免疫球蛋白類蛋白質分離純化的色譜介質及其制備方法,中國發明專利,ZL 200710059576.5

          (9) 徐亮,董曉燕,史清洪,白姝,孫 彥:陰離子聚合物接枝涂層毛細管及用于蛋白質在線富集分析方法,中國發明專利,ZL 200810151254.8

          (10) 徐亮,孫 彥,史清洪,白姝,董曉燕:聚乙烯醇涂層毛細管的制備方法及應用,中國發明專利,ZL 200910067986.3

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